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	<title>Comments on: Treating Crohn&#8217;s with stem cells</title>
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	<link>http://eatingscd.com/2009/02/20/treating-crohns-with-stem-cells/</link>
	<description>Treating my Crohn&#039;s with the Specific Carbohydrate Diet</description>
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		<title>By: Chris</title>
		<link>http://eatingscd.com/2009/02/20/treating-crohns-with-stem-cells/#comment-370</link>
		<dc:creator><![CDATA[Chris]]></dc:creator>
		<pubDate>Fri, 27 Feb 2009 03:38:47 +0000</pubDate>
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		<description><![CDATA[According to the information I&#039;ve read concerning both treatments, autologus stem cell transplant and a mesenchymal stem cell transplant like Prochymal, is a documented failed response to steroids, immune suppressants, and at least one biologic like Remicade or Humira. I know from my research only 15-20 persons have received a stem cell transplant directly because of Crohn&#039;s.  Most other persons who the universities in the U.S. are basing their research off of, received a transplant as treatment for some other ailment.

From the forums I&#039;ve seen regarding Prochymal, it has all been very promising.  As Prochymal is in Phase 3 trials, it&#039;s randomized, double blinded, placebo controlled study.  Those participatin in the trials receiver either a full dose of Prochymal (showed maximum results i.e. decease remission in 28 days of first infusion and document mucosa healing); a half dosage (again showed great results); or the placebo.  Again, the only side effect Prochymal has documented is that patients smell like an onion for 2-3 days after their infusions because of the preservatives used.

I love SCD!  However, it&#039;s my belief that when Prochymal gets approved, it in combination with SCD will be what so many IBD patient have been looking for!]]></description>
		<content:encoded><![CDATA[<p>According to the information I&#8217;ve read concerning both treatments, autologus stem cell transplant and a mesenchymal stem cell transplant like Prochymal, is a documented failed response to steroids, immune suppressants, and at least one biologic like Remicade or Humira. I know from my research only 15-20 persons have received a stem cell transplant directly because of Crohn&#8217;s.  Most other persons who the universities in the U.S. are basing their research off of, received a transplant as treatment for some other ailment.</p>
<p>From the forums I&#8217;ve seen regarding Prochymal, it has all been very promising.  As Prochymal is in Phase 3 trials, it&#8217;s randomized, double blinded, placebo controlled study.  Those participatin in the trials receiver either a full dose of Prochymal (showed maximum results i.e. decease remission in 28 days of first infusion and document mucosa healing); a half dosage (again showed great results); or the placebo.  Again, the only side effect Prochymal has documented is that patients smell like an onion for 2-3 days after their infusions because of the preservatives used.</p>
<p>I love SCD!  However, it&#8217;s my belief that when Prochymal gets approved, it in combination with SCD will be what so many IBD patient have been looking for!</p>
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		<title>By: sharon</title>
		<link>http://eatingscd.com/2009/02/20/treating-crohns-with-stem-cells/#comment-368</link>
		<dc:creator><![CDATA[sharon]]></dc:creator>
		<pubDate>Fri, 27 Feb 2009 01:39:04 +0000</pubDate>
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		<description><![CDATA[This is actually a question.... what is the determining factor used in the decision to bring your treatment to this level?                           Thanks]]></description>
		<content:encoded><![CDATA[<p>This is actually a question&#8230;. what is the determining factor used in the decision to bring your treatment to this level?                           Thanks</p>
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		<title>By: Chris</title>
		<link>http://eatingscd.com/2009/02/20/treating-crohns-with-stem-cells/#comment-364</link>
		<dc:creator><![CDATA[Chris]]></dc:creator>
		<pubDate>Fri, 20 Feb 2009 23:44:33 +0000</pubDate>
		<guid isPermaLink="false">http://eatingscd.wordpress.com/?p=1132#comment-364</guid>
		<description><![CDATA[They are actually doing this in the United States as well.  At the University of North Carolina and at Northwestern Memorial in IL. There have been several Crohn&#039;s patients who have received this treatment and retained long term remission.  Some claim 10 years plus.  However, this obviously does not address the cause of our disease.  Canada and the U.K. have similar studies/treatments going on as well.

There is also another treatment that uses donor cells currently in Phase III trials.  It&#039;s called Prochymal.  The makers of Prochymal boast there are no side effects from there treatment which is given over the course of 4 IV infusions over a 2 week period.  Prochymal is supposed to induce disease remission and mucosa healing.  The treatment has recently received approval for use in Graft vs. Host Disease and is supposed to be the next treatment of choice for moderate to severe Crohn&#039;s Disease. The FDA has given it &quot;Fast Track Approval&quot; status as the results of the Phase II trials were so promising.]]></description>
		<content:encoded><![CDATA[<p>They are actually doing this in the United States as well.  At the University of North Carolina and at Northwestern Memorial in IL. There have been several Crohn&#8217;s patients who have received this treatment and retained long term remission.  Some claim 10 years plus.  However, this obviously does not address the cause of our disease.  Canada and the U.K. have similar studies/treatments going on as well.</p>
<p>There is also another treatment that uses donor cells currently in Phase III trials.  It&#8217;s called Prochymal.  The makers of Prochymal boast there are no side effects from there treatment which is given over the course of 4 IV infusions over a 2 week period.  Prochymal is supposed to induce disease remission and mucosa healing.  The treatment has recently received approval for use in Graft vs. Host Disease and is supposed to be the next treatment of choice for moderate to severe Crohn&#8217;s Disease. The FDA has given it &#8220;Fast Track Approval&#8221; status as the results of the Phase II trials were so promising.</p>
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	<item>
		<title>By: afragogrunner</title>
		<link>http://eatingscd.com/2009/02/20/treating-crohns-with-stem-cells/#comment-363</link>
		<dc:creator><![CDATA[afragogrunner]]></dc:creator>
		<pubDate>Fri, 20 Feb 2009 19:26:11 +0000</pubDate>
		<guid isPermaLink="false">http://eatingscd.wordpress.com/?p=1132#comment-363</guid>
		<description><![CDATA[Very helpful. I might be interning on a stem cell transplant/oncology unity and this is exactly what the interviewer talked about. Sounds intense, and like you said it is.]]></description>
		<content:encoded><![CDATA[<p>Very helpful. I might be interning on a stem cell transplant/oncology unity and this is exactly what the interviewer talked about. Sounds intense, and like you said it is.</p>
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