New research re: antibiotics affect on your microbiome

An AP article in the Washington Post raises questions about the long term affects of repeated antibiotic use.

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3 Responses to “New research re: antibiotics affect on your microbiome”


  1. 1 Eva Paterson September 15, 2010 at 9:54 am

    Thanks for posting a link to this article, Paul.
    In the article it says they are considering “a theory that early use of antibiotics disrupts the developing microbiome in ways that spur autoimmune disorders.”
    My daughter (diagnosed about 2 years ago with Crohn’s – SCD for 18 months and symptom /drug free) was given a round of antibiotics when she was just less than 1 year old. Since the Crohn’s diagnosis I’ve often thought of that round of early antibiotics and what it did to her gut.
    I’m also wondering about her testing positive for salmonella just before the colonoscopy that diagnosed Crohn’s. Maybe she was lacking the essential bacteria that would help her fight Salmonella?
    Anyway, thanks again for sharing your research.
    Right now she is doing great. She’s getting married this weekend (SCD compliant wedding cake, of course) to a wonderful young man and just completed a local charity event along the lines of the Amazing Race. SHE is AMAZING!!
    Cheer’s,
    Eva Paterson

    • 2 Paul Stocker September 23, 2010 at 3:53 pm

      Eva,

      You’re welcome.

      It seems entirely possible, especially if she was genetically predisposed. We have a friend who’s daughter developed ulcerative colitis as a baby. This was shocking to me as I had never heard of someone so young with that disease. It turns out that she had had significant rounds of antibiotics as well. It’s hard to write that off as a coincidence. I think a round of penicillin when I was a pre-teen may have been the final straw for me.

      As an aside, the method of birth plays a part in your babies microbiome. Here’s the study report: http://esciencenews.com/articles/2010/06/21/babies.first.bacteria.depend.birthing.method.says.new.study

      I have two daughters. The oldest was born by C-section and the youngest normally. The youngest has the more robust immune system that is pretty good at fighting off illness. In contrast, the oldest is prone to high spiking fevers and longer illness so we have to watch her very carefully. I’m convinced their birth method is involved in this.

      The debate over specific bacterias versus the microbiome as a whole as causitive for IBD is still raging, but the scientific community as a whole seem to agree that the quality and state of our microbiome is very important for our health.

      Congratulations on the wedding! I bet you are very proud.

      -Paul

  2. 3 Gerald at crohns help September 27, 2010 at 5:23 pm

    If you do some rsearch or just Google (crohns disease yeast infection ) You will find that some researchers link either early antibiotic use or broadspectrum antibiotic use before the diseases appear. It seems that antibiotic use suppresses the immune system-
    intestinal flora ( the good bacteria ) as well as the bad guys leaving the yeast a free rein to grow out of hand.

    Even in some cases some doctors give the possibility that antibiotic suppression of the immune system may be the cause of lukemia. Check out
    http://www.cancerfightingstrategies.com/fungalconnection.html


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