Archive for the 'research' Category

uBiome – get your microbiome sequenced

This looks interesting:

Be a citizen scientist and help us sequence the human microbiome. Learn about your health, advance science, and CHANGE THE WORLD!

Here’s your link.

Specific bacterial species may initiate, maintain Crohn’s

From the study:

Patients newly diagnosed with pediatric Crohn’s disease had significantly different levels of certain types of bacteria in their intestinal tracts than age-matched controls, according to a paper in the October Journal of Clinical Microbiology. The work may ultimately lead to treatment involving manipulation of the intestinal bacteria.

Here’s the link to an easy to read version. And here’s your link to the actual study report.

Thanks to Ryan Jordan on Facebook. You should get Ryan’s posts on your feed as he’s really on top of research and news on Crohn’s.

Randomized drug trials not so randomized

In this meta study, only about one third of IBD patients reviewed would have been eligible to participate in FDA studies on the efficacy of biological agents (Adalimumab, Certolizumab pegol, Infliximab, Natalizumab, etc.) for IBD.

Most patients with moderate–severe IBD evaluated in an outpatient practice would not qualify for enrollment in a pivotal RCT of biological reagents; this finding raises important questions about their therapeutic efficacy beyond the clinical trial populations.

Here’s your link.


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