Because Crohn's sucks
Article From Scientific American:
The largest study of its kind has revealed for the first time the specific gut bacteria involved in Crohn’s disease, which afflicts an estimated 700,000 Americans with chronic, painful diarrhea and bleeding, among other unpleasant symptoms. With a better understanding of how the microbial ecosystem changes in children who suffer from the disease, researchers have gained clues that could someday lead to better diagnosis and treatment.
The Crohn’s and Colitis Foundation of America has released it’s latest “Challenges in IBD Research” It is from their official journal and is entitled “Update on Progress and Prioritization of the CCFA’s Research Agenda“. Unfortunately, most of the content of this site is behind a paywall, but this particular report is free.
A report from UC Davis Health System links nitrate produced by gut inflammation to E. coli growth, crowding out good bacteria, and contributing to the inflammatory process.
In test-tube and animal studies, the researchers found that potentially harmful bacteria in the intestine called Enterobacteriaceae use nitrate — a byproduct formed during the intestinal inflammation in IBD — to grow and thrive. Enterobacteriaceaestrains include certain E. coli bacteria, which can worsen the intestinal damage of IBD. Eventually, the intestines of those with IBD become overrun by harmful bacteria, and the numbers of normal good bacteria in the gut decrease.
Here’s your link.
